Kehaulani, I've no doubt about masterpieces existing that have been earlier printed, and even before the printing press, put down in ink tediously, by monk for the church or clerk / scribe for their patron, but all of these are copies of an original manuscript prepared in lesser or more portable media. Also, there are exceptions where the actual composer never put to paper or other surface a single note for posterity, just as one example: Irving Berlin. During WWII, I was a copyist - transcriber - transposer, as others in our HS band were also, when printed music then wasn't very much available for us, especially so, much from other countries. That experience has kept me in good stead ever since and is not what I hope I'll never need to do again ... but notice that in many impoverished areas of the world they too must "make do" however they can. Certainly, I've seen pencil marks of about everything on pre-owned music that I've scrounged and/or acquired and had to wear out a few erasers to clean them up.