Mark, true enough. Kalydeco is a real miracle drug and the combination study with the Delta 508 will likely change CF into a completely "curable" disease. However, keeping the airways open for EVERYONE with or without pulmonary disease I believe will maintain pulmonary function in all of us. And I agree, trumpet is a great airway clearance technique for COPD as well. Mark, I will let you know the next time my quintet is in Cincinnati or N. Ky. We were playing at the Thompson House regularly earlier in the year, but the jazz venue closed there. Would love to hear your stories of your trumpet playing, and would LOVE to have you sit in with the band. What a true honor that would be for me. If you ever go through the CF Clinic in Cincy, give Patricia Joseph a fond hello for me. She is such a gifted pulmonologist and a jazz fan as well. She came out to her our quintet when we were playing at The Redmore.