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The resistance is only harmful when you try and blow the mute up.

The most productive practice with any practice mute is done playing softly. The resistance that you perceive comes from 2 places, the slightly increased airflow restriction and your brain trying to capture audible signals/feedback and telling your body to blow harder. This is the same source of "stuffiness" when we play a horn unmuted outdoors at a lake or big field where there is no echo!
A relaxed approach makes this mute magic. Anything less can make it hell!

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Whenever I feel blue, I start breathing again.