The amount of effort required to have a successful career in one's chosen field is not that much different from choice "A" to choice "B" to choice "C". But the difference in the end is the financial reward. Any professional career will require years of hard work, dedication and sacrifice, plus a bit of chance taking. And money is not the answer to happiness, but it comes in a close second.
In the end you make your decision...then you live with it, for better or for worse. Kinda like getting married.